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| Description |
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SMuFin (Somatic MUtation FINder) is a reference-free method designed to identify somatic variation on tumor genomes from the direct comparison with the corresponding normal genome of the same patient. Through a single execution SMuFin is able to identifying somatic single nucleotide variants (SNVs) and structural variants (SVs) of any size.
The current version of the program cannot detect complete losses of chromosome arms, variants flanked by palindromic sequences or copy number variants (CNVs) at quantitative level.
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| SMuFin is described in detail at: |
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Reference: Moncunill V. & Gonzalez S., et al. Comprehensive characterization of complex structural variations in cancer by directly comparing genome sequence reads. Nature Biotechnology, 2014; 10.1038/nbt.3027. |
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| Additional Supplementary Material: |
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